ACE inhibitors and ARBs can cause severe fetal harm during pregnancy, including kidney damage and miscarriage. Learn why these blood pressure meds are dangerous and what safer alternatives like labetalol and methyldopa are recommended by leading medical groups.
Cholestatic pruritus is a severe, non-histamine-related itching caused by liver bile buildup. Bile acid resins like cholestyramine are first-line, but newer drugs like maralixibat offer better tolerability and effectiveness. Learn what works, what doesn't, and what's coming next.
Colchicine can become deadly when taken with certain macrolide antibiotics like clarithromycin due to CYP3A4 and P-gp inhibition. Learn which antibiotics are safe, how toxicity develops, and what to do if you're at risk.
Genetic differences can make medications dangerous for some people and useless for others. Learn how specific gene variants like CYP2D6 and HLA-B*15:02 affect drug reactions-and what you can do about it.
Learn how to read the updated FDA pregnancy and lactation drug labels that replaced outdated letter categories. Understand risk summaries, breastfeeding exposure, and clinical guidance for safer medication use during pregnancy and nursing.
Learn when to use OTC medications versus prescription drugs for common conditions like headaches, allergies, and heartburn. Understand safety, cost, and when to see a doctor.
Your chronotype - whether you're a morning lark or night owl - shapes your sleep, health, and productivity. Learn how to align your schedule with your biology for better energy, focus, and long-term well-being.
Milk thistle can interfere with liver-metabolized drugs by altering CYP enzyme activity, potentially raising or lowering medication levels. Learn which drugs are at risk and how to stay safe.
Menopause hormone therapy can relieve hot flashes, night sweats, and bone loss-but only if used correctly. Learn who benefits, who should avoid it, and how to start safely based on the latest 2025 guidelines.
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