Furosemide: Uses, How It Works, Dosing, and Safety
Furosemide is a powerful diuretic that helps your body get rid of extra salt and water. Doctors prescribe it most often for fluid buildup from heart failure, liver disease, or kidney problems. It also helps control blood pressure when other drugs aren’t enough. You’ll see it as an oral tablet, oral liquid, or an IV injection in hospitals.
How furosemide works and when to take it
Furosemide blocks salt reabsorption in the kidney, so your body makes more urine and removes fluid. You usually notice fewer swollen ankles or less shortness of breath within hours after a dose. For chronic use, doctors set a daily dose—sometimes once a day, sometimes split into two doses. In acute cases, such as sudden fluid overload, medical staff give it by IV for faster effect.
Take furosemide in the morning if possible to avoid waking at night to urinate. If you must take a second dose, take it early afternoon. Always follow your prescriber’s instructions; doses range widely depending on the condition and how well the kidneys work.
Side effects, interactions, and monitoring
The common side effects are increased urination, dehydration, low potassium or sodium, dizziness, and low blood pressure. Less common but serious effects include kidney function changes and hearing problems, especially with rapid IV doses or high amounts. Because of electrolyte loss, your doctor will usually check blood tests after starting or changing a dose. If you feel very dizzy, faint, or notice ringing in your ears, contact a clinician right away.
Furosemide interacts with several drugs. NSAIDs can blunt its effect, while ACE inhibitors or ARBs can increase risks of low blood pressure or kidney issues. Combining furosemide with other blood pressure medicines raises the risk of fainting. Some antibiotics and drugs that affect hearing or electrolytes may add risk. Tell your provider about all medicines, supplements, and salt substitutes you use.
Special precautions matter. In pregnancy and breastfeeding, use only if a doctor says it’s necessary. If you have diabetes or gout, furosemide may affect blood sugar or uric acid. People with very low blood pressure or severe kidney dysfunction need close supervision.
How to store and refill: keep tablets in a cool, dry place away from children. Don’t stop suddenly without medical advice—your fluid levels and blood pressure can change quickly. If you miss a dose, take it when you remember unless it’s close to the next dose; don’t double up.
Seek emergency care if you have fainting, severe lightheadedness, fast heartbeat, little or no urine, sudden hearing loss, or severe rash. Keep a list of questions: Is my dose right for my kidneys? Do I need potassium or sodium checks? Can this drug affect my other conditions? Bring this list to your visit.
If you want to learn more, ask your pharmacist for a leaflet or speak to your prescriber. Simple steps—monitoring weight, checking blood tests, and noting symptoms—help you use furosemide safely and get the benefits without surprise problems.